The Abramson Family Cancer Research Institute at the University of Pennsylvania Cancer Center

Cells of Aggressive Leukemia Hijack Normal Protein to Grow, According to Penn Study

PHILADELPHIA - Researchers have found that one particularly aggressive type of blood cancer, mixed lineage leukemia (MLL), has an unusual way to keep the molecular motors running. The cancer cells rely on the normal version of an associated protein to stay alive. (more)

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Leonard and Madlyn Abramson, The Abramson Family Cancer Research Institute

In the ten years since the Abramson family's original gift of $100 million established the Abramson Family Cancer Research Institute at the University of Pennsylvania, the Institute has been recognized as one of the elite cancer research programs in the country. Their gift has transformed the culture of clinical care at the Abramson Cancer Center to a patient-centered approach.

Due to the vision and support of Madlyn and Leonard Abramson, the institute has evolved from a handful of newly recruited investigators to an internationally recognized and respected group of physician scientists. Nationally renowned cancer investigators have been recruited and retained; currently, the Institute has 33 faculty members, including Dr. M. Celeste Simon, the new Scientific Director. Dr Simon, Professor of Cell and Developmental Biology, was recently re-appointed as a Howard Hughes Medical Institute Investigator, one of the highest recognitions of scientific excellence in the United States.

The Abramson Cancer Center encompasses an institute for scientific inquiry working alongside a cutting-edge clinical care operation. The interactions between the Institute and the Abramson Cancer Center have accelerated basic and translational research initiated through the Institute into new prevention diagnosis, and treatment programs at the Cancer Center. With the planned construction projects at PENN Medicine, the symbiosis between the Institute and the Cancer Center will be even further enhanced as they are united within a physical structure embodying their interactive philosophy.